A focused evaluation of iron metabolism and storage. Measures serum iron, total iron-binding capacity (TIBC), transferrin saturation, and ferritin levels. Essential for diagnosing iron deficiency anemia, iron overload conditions (hemochromatosis), and monitoring iron supplementation therapy. Helps distinguish between iron deficiency and anemia of chronic disease.
This panel answers a question that a single iron test cannot: not just how much iron is circulating right now, but how much is stored and how effectively your body is transporting and using it. Serum iron and transferrin saturation capture the moment-to-moment supply, ferritin reflects your long-term iron reserves, and TIBC and transferrin show how much carrying capacity your body has built in response to demand. The soluble transferrin receptor adds a key advantage: because it rises with true tissue iron need but is largely unaffected by inflammation, it helps distinguish genuine iron deficiency from the low readings seen in anemia of chronic disease—a distinction that ferritin alone can obscure. Together these markers can flag depleted stores before anemia develops, help clarify whether fatigue is iron-related, and support monitoring during supplementation or investigation of iron overload. Running all five measures from a single blood draw is both more convenient and more interpretable than ordering them piecemeal, since they are most meaningful when read against one another. The results give you and your clinician a fuller, more actionable picture than any one value in isolation.
For athletes & active people
Iron status is particularly relevant for endurance and high-volume athletes, who can lose iron through foot-strike hemolysis, sweat, and increased turnover, while also facing greater oxygen-carrying demands during training and recovery. Low iron stores can blunt adaptation and contribute to persistent fatigue even before hemoglobin drops, so tracking ferritin and true tissue need alongside transport markers can help you catch a problem early. Because ferritin also rises with the inflammation of hard training, pairing it with soluble transferrin receptor gives athletes a clearer read on whether stores are genuinely low.
Order online
Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.
Get your sample collected
Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).
See your results
Your results land in your Insider portal, ready to review and act on — that easy.
Insider panel price
$58.71$270
4.6× less than retail
Versus the typical direct-to-consumer retail cost of ordering these tests individually (illustrative — consumer prices vary by provider and region). Your $20 order fee is waived as an Insider.
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