Follicle Stimulating Hormone (FSH) is a glycoprotein gonadotropin secreted by the anterior pituitary gland under the regulation of hypothalamic gonadotropin-releasing hormone (GnRH). In females, FSH stimulates follicular growth and estrogen production in the ovaries; in males, it supports spermatogenesis by acting on Sertoli cells. FSH levels are a critical component of the hypothalamic-pituitary-gonadal (HPG) axis and are widely used to assess reproductive and endocrine function. FSH release is pulsatile and regulated by GnRH stimulation and negative feedback from gonadal hormones, primarily estradiol and inhibin B. In females, FSH rises during the early follicular phase, triggering follicular recruitment, and surges mid-cycle to facilitate ovulation alongside LH. In males, FSH acts on Sertoli cells to promote spermatogenesis and is suppressed by inhibin B produced within the testes.
FSH is a hormone made by the pituitary gland in the brain that plays an important role in reproduction. In women, it helps control the menstrual cycle and egg development; in men, it supports sperm production. When FSH is higher than normal, it may mean the ovaries or testes are not responding as expected, which can affect fertility. When FSH is lower than normal, it may suggest the brain is not sending the right signals to the reproductive organs. Your doctor will look at FSH alongside other hormones and your overall health to understand what the result means for you.
When elevated: Elevated FSH suggests primary gonadal insufficiency, diminished ovarian reserve, premature ovarian insufficiency, or menopause in women. In men, high FSH may indicate primary testicular failure or Klinefelter syndrome. Persistently elevated FSH warrants further evaluation of gonadal function and fertility potential. When low: Low FSH levels suggest hypothalamic or pituitary dysfunction, including hypogonadotropic hypogonadism, hyperprolactinemia, or suppression from exogenous hormones. Low FSH may also be seen in conditions of chronic illness, significant weight loss, or excessive exercise that disrupt the HPG axis. This pattern requires evaluation of the entire pituitary-gonadal axis.
FSH is less directly relevant to athletic performance than testosterone or cortisol, but it reflects reproductive and hormonal health—both important for sustained training capacity and recovery. Chronically elevated training stress, low energy availability, or overtraining can suppress the HPG axis and lower FSH, signaling potential reproductive strain; monitoring FSH alongside other hormones helps athletes maintain hormonal balance for long-term health and fertility.
Turnaround Time
3 days (up to 13 days)
Fasting Required
No
Order online
Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.
Get your sample collected
Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).
See your results
Your results land in your Insider portal, ready to review and act on — that easy.
Your price
$5.00$60
12.0× less than retail
Versus the typical direct-to-consumer retail price for this test (illustrative — consumer prices vary by provider and region).
$5.00
$8.98
$27.50
Peer-reviewed sources supporting the educational content on this page.