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Biomarkerallergy

Food Allergy Profile

The Food Allergy Profile (BioReference) is a panel of allergen-specific immunoglobulin E (IgE) antibody measurements directed against a curated set of common food allergens, performed by BioReference Laboratories using fluorescent enzyme immunoassay (FEIA) or similar quantitative platforms. It is used to identify sensitization to foods such as peanut, tree nuts, milk, egg, wheat, soy, shellfish, and fish, supporting the clinical evaluation of IgE-mediated food hypersensitivity. Results must be interpreted in the context of clinical history, symptoms, and, when appropriate, confirmatory oral food challenge. IgE-mediated food allergy involves sensitization whereby initial allergen exposure drives B-cell class switching to produce allergen-specific IgE antibodies, which bind to high-affinity FcεRI receptors on mast cells and basophils. Upon re-exposure, cross-linking of receptor-bound IgE by the allergen triggers degranulation and release of histamine, leukotrienes, and cytokines, producing the hallmark symptoms of immediate hypersensitivity. The magnitude of allergen-specific IgE (measured in kUA/L) reflects the degree of humoral sensitization but does not directly quantify clinical reactivity or reaction severity.

From $250.00schedule~5d resultsbiotechAvailable at Quest · BioReference
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What this test reveals

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This blood test checks whether your immune system has made allergy antibodies (IgE) against specific foods. A positive result means your immune system has reacted to that food, but your doctor will need to review your symptoms and history to determine whether you are truly allergic.

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What abnormal values may indicate

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When elevated: Elevated allergen-specific IgE (particularly above established decision points, e.g., ≥15 kUA/L for milk in children or ≥14 kUA/L for egg) is associated with a high probability of clinical reactivity and may support avoidance recommendations pending specialist evaluation. Very high levels for certain allergens (e.g., peanut-specific IgE >15 kUA/L) have been associated with increased risk of severe reactions, though level alone does not reliably predict anaphylaxis severity. Referral to an allergist for comprehensive evaluation, including consideration of component-resolved diagnostics and supervised oral food challenge, is generally warranted. When low: Low or undetectable allergen-specific IgE substantially reduces the probability of IgE-mediated allergy to that food and may support cautious reintroduction under appropriate clinical guidance. However, a negative specific-IgE does not rule out non-IgE-mediated immune reactions (e.g., food protein-induced enterocolitis syndrome, eosinophilic esophagitis) or pharmacologic/toxic food reactions. In patients with a compelling clinical history despite negative serology, skin prick testing or supervised oral food challenge may be necessary.

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For athletes

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Food allergies can trigger immediate systemic reactions—including anaphylaxis—that interrupt training and competition, and chronic GI symptoms may impair nutrient absorption and recovery. Athletes should know their allergen status to avoid inadvertent exposure during travel, competition nutrition, or team meals, and to distinguish true IgE-mediated allergy from food intolerance or sensitivity.

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Turnaround Time

5 days (up to 6 days)

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Fasting Required

No

scienceExpected Results

15 results
Sesame Seed (F10) IgePeanut (F13) IgeAlmond (F20) IgeCodfish (F3) IgeShrimp (F24) IgeScallop (F338) IgeTuna (F40) IgeEgg White (F1) IgeCows Milk (F2) IgeWheat (F4) IgeSoybean (F14) IgeHazelnut (F17) IgeSalmon (F41) IgeCashew Nut (F202) IgeWalnut (F256) Ige
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How it works

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    Order online

    Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.

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    Get your sample collected

    Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).

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    See your results

    Your results land in your Insider portal, ready to review and act on — that easy.

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Your price

$250.00$750

Save ~$500

3.0× less than retail

Versus the typical direct-to-consumer retail price for this test (illustrative — consumer prices vary by provider and region).

BioReferenceBest price

$250.00

Quest

$550.00

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References (3)

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Peer-reviewed sources supporting the educational content on this page.

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