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Biomarkerheavy metals

Heavy Metals Profile, Blood (3)

The Heavy Metals Profile, Blood (3) is a laboratory panel that measures concentrations of multiple toxic heavy metals—typically including lead, mercury, and arsenic—in whole blood or serum. This panel is used to assess occupational, environmental, or dietary exposure to potentially harmful metallic elements. Results are interpreted in the context of clinical history, exposure risk, and established reference ranges from regulatory and public health bodies. Heavy metals such as lead, mercury, and arsenic are not essential to normal human physiology and exert toxicity by displacing essential minerals, inhibiting enzymatic activity, and generating oxidative stress at the cellular level. Once absorbed through inhalation, ingestion, or dermal contact, these metals distribute to blood, soft tissues, and bone, with variable half-lives ranging from days (blood mercury) to decades (skeletal lead). The body has limited capacity to detoxify or excrete heavy metals, making bioaccumulation a significant concern with chronic low-level exposure.

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What this test reveals

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This blood test checks for the presence of harmful heavy metals—such as lead, mercury, and arsenic—in your bloodstream. These substances are not naturally needed by the body and can cause health problems if they build up over time from sources like certain foods, water, or workplace exposures. The test helps identify whether you have been recently exposed to these metals at levels that may be concerning. Your healthcare provider will review your results alongside your personal history to determine if any follow-up is needed. Low or undetectable levels are generally reassuring, while elevated levels may prompt further evaluation or steps to reduce exposure.

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What abnormal values may indicate

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When elevated: Elevated blood heavy metal levels indicate significant recent or ongoing exposure and are associated with a spectrum of adverse health effects depending on the metal, level, and duration of exposure. High lead levels are linked to neurodevelopmental impairment in children and cardiovascular, renal, and neurological effects in adults. Elevated mercury is associated with neurological symptoms, sensory disturbances, and renal toxicity. Elevated arsenic raises concern for peripheral neuropathy, skin changes, and increased risk of certain malignancies with chronic exposure. When low: Low or undetectable blood heavy metal levels generally indicate absence of significant recent exposure and are reassuring in the context of occupational or environmental screening. However, low blood levels do not exclude past exposure or significant tissue/bone burden, particularly for lead, which redistributes from blood to bone over time. Clinical correlation remains essential, as symptoms of chronic toxicity may persist despite declining blood levels.

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For athletes

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Heavy metals are not primarily an athletic performance marker; however, endurance athletes and those training outdoors (cyclists, trail runners, rowers) may face elevated inhalation exposure to traffic-related lead and mercury, while coastal athletes might encounter higher seafood-derived mercury intake. Monitoring this panel is relevant mainly for athletes in high-exposure occupations or environments rather than as a routine performance or recovery metric.

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Turnaround Time

3 days (up to 7 days)

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Fasting Required

No

scienceExpected Results

3 results
Mercury, Whole BloodArsenic, BloodLead, Blood (Adult)
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How it works

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    Order online

    Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.

  2. 2location_on

    Get your sample collected

    Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).

  3. 3monitoring

    See your results

    Your results land in your Insider portal, ready to review and act on — that easy.

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Your price

$275.00$825

Save ~$550

3.0× less than retail

Versus the typical direct-to-consumer retail price for this test (illustrative — consumer prices vary by provider and region).

BioReference

$275.00

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References (3)

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Peer-reviewed sources supporting the educational content on this page.

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