Pregnenolone is a steroid hormone produced by the adrenal glands and gonads; it serves as a precursor to other hormones like DHEA, progesterone, and cortisol. This test measures pregnenolone levels to assess adrenal function and hormone balance.
Pregnenolone is a steroid hormone produced by the adrenal glands and gonads; it serves as a precursor to other hormones like DHEA, progesterone, and cortisol. This test measures pregnenolone levels to assess adrenal function and hormone balance.
When elevated: Elevated pregnenolone may indicate adrenal hyperactivity, congenital adrenal hyperplasia (CAH), or certain adrenal tumors. It can also reflect increased stress or stimulation of the adrenal glands. When low: Low pregnenolone may suggest adrenal insufficiency, chronic stress with adrenal fatigue, or reduced production of steroid hormones. It can also occur with aging or certain medications that suppress adrenal function.
Pregnenolone is a foundational steroid hormone that influences recovery, immune function, and stress resilience during heavy training. Athletes under sustained training stress may show altered pregnenolone levels; monitoring it can help assess whether adrenal capacity is keeping pace with training demands and whether recovery strategies are adequate.
Turnaround Time
3 days (up to 10 days)
Method
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
verifiedGold StandardMass spectrometry — higher accuracy, especially at low concentrations
Order online
Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.
Get your sample collected
Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).
See your results
Your results land in your Insider portal, ready to review and act on — that easy.
Your price
$38.90$115
3.0× less than retail
Versus the typical direct-to-consumer retail price for this test (illustrative — consumer prices vary by provider and region).
$38.90
Peer-reviewed sources supporting the educational content on this page.
Pregnenolone is a steroid hormone produced by the adrenal glands and gonads; it serves as a precursor to other hormones like DHEA, progesterone, and cortisol. This test measures pregnenolone levels to assess adrenal function and hormone balance.
Pregnenolone is a steroid hormone produced by the adrenal glands and gonads; it serves as a precursor to other hormones like DHEA, progesterone, and cortisol. This test measures pregnenolone levels to assess adrenal function and hormone balance.
When elevated: Elevated pregnenolone may indicate adrenal hyperactivity, congenital adrenal hyperplasia (CAH), or certain adrenal tumors. It can also reflect increased stress or stimulation of the adrenal glands.
The Pregnenolone, Mass Spectrometry (Endocrine Sciences) test starts at $38.90 at Labcorp. No doctor's visit and no insurance needed; we do not bill insurance. Fitomics Insider members pay from $32.90.
Results for the Pregnenolone, Mass Spectrometry (Endocrine Sciences) test are typically ready about 3 days after your draw, and up to 10 days for some samples. Your results land in your Insider portal.
No. When you order the Pregnenolone, Mass Spectrometry (Endocrine Sciences) test from Fitomics Research Labs, a licensed physician in our 50-state network reviews and signs your requisition after checkout, and it lands in your portal and inbox. Then visit any Labcorp, Quest, or BioReference patient service center for your draw; results post to your Insider portal.
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