Login
Biomarkervitamins minerals

Vitamin A (Retinol), Serum

Vitamin A (retinol) is a fat-soluble micronutrient essential for vision, immune function, cellular differentiation, and epithelial integrity. Serum retinol concentration is the most commonly used clinical measure of vitamin A status, though it is a relatively insensitive indicator of body stores due to homeostatic regulation by the liver. Plasma retinol levels are maintained within a narrow range until hepatic reserves are substantially depleted or overwhelmed. Dietary vitamin A is obtained as preformed retinol from animal sources or as provitamin A carotenoids (e.g., beta-carotene) from plant sources, both of which are absorbed in the small intestine and stored predominantly in hepatic stellate cells. Retinol is mobilized from the liver bound to retinol-binding protein (RBP) and transthyretin for transport to peripheral tissues, where it is converted to active metabolites including retinal (critical for phototransduction) and retinoic acid (a nuclear receptor ligand regulating gene expression). Vitamin A status is tightly regulated by the liver, meaning serum retinol may appear normal even when hepatic stores are significantly reduced.

From $25.00schedule~9d resultsbiotechAvailable at Labcorp · Quest · BioReference
verifiedCLIA-certified labsmedical_services50-state physician networklocation_on4,000+ draw locations
See pricing & orderarrow_downward
lightbulb

What this test reveals

expand_more

Vitamin A is a nutrient your body needs for healthy vision (especially in low light), a strong immune system, and maintaining healthy skin and tissues. Your blood level of vitamin A (called retinol) can be measured to check whether you are getting too little or too much. Too little vitamin A can cause difficulty seeing at night, increased infections, and in severe cases, eye damage. Too much—usually from high-dose supplements rather than food—can be harmful to the liver and bones, and is especially dangerous during pregnancy. Your doctor will interpret your result alongside your diet, health history, and other lab values.

warning

What abnormal values may indicate

expand_more

When elevated: Elevated serum retinol may indicate vitamin A toxicity (hypervitaminosis A), which can manifest as hepatotoxicity, pseudotumor cerebri, bone pain, alopecia, and teratogenic risk in pregnancy. Chronic excess is associated with reduced bone mineral density and increased fracture risk. When low: Low serum retinol is associated with night blindness (nyctalopia), xerophthalmia, increased susceptibility to infections (particularly measles and respiratory infections), impaired growth in children, and poor wound healing. Severe deficiency can progress to corneal ulceration and irreversible blindness.

exercise

For athletes

expand_more

Vitamin A supports immune function and epithelial repair, which can be stressed by intense training and environmental exposure. Adequate status may help maintain mucosal barriers and reduce upper-respiratory infection risk during heavy training blocks, though serum retinol alone is an insensitive marker of total body stores.

schedule

Turnaround Time

9 days (up to 13 days)

restaurant_menu

Fasting Required

No

scienceExpected Results

1 result
Vitamin A
route

How it works

  1. 1shopping_cart

    Order online

    Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.

  2. 2location_on

    Get your sample collected

    Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).

  3. 3monitoring

    See your results

    Your results land in your Insider portal, ready to review and act on — that easy.

shopping_cart

Choose your lab & order

Your price

$25.00$75

Save ~$50

3.0× less than retail

Versus the typical direct-to-consumer retail price for this test (illustrative — consumer prices vary by provider and region).

LabcorpBest price

$25.00

BioReference

$25.00

Quest

$29.90

menu_book

References (3)

expand_more
Continue shopping in the Lab Shoparrow_forward