Comprehensive hormonal assessment for both men and women. Evaluates sex hormones (estradiol, progesterone, testosterone), DHEA-S, SHBG, and pituitary hormones (FSH, LH). Essential for assessing hormonal balance, fertility evaluation, and identifying hormonal imbalances affecting health and well-being.
This panel measures the core sex hormones and the pituitary signals that regulate them, so you can see not just hormone levels but how the whole axis is working together. Testosterone (total and free) and estradiol tell you about circulating hormone activity, while SHBG explains how much of that testosterone is actually bioavailable versus bound and inactive — a low or high SHBG can dramatically change what a total testosterone number means. FSH and LH reflect the pituitary's signaling to the gonads, which helps distinguish whether a low sex-hormone level originates in the testes/ovaries or in the brain's control center — a distinction a single hormone test cannot make. Because these markers are interpreted in context of one another, this combination answers practical questions about libido, energy, menstrual regularity, fertility, and recovery that isolated tests leave ambiguous. The estradiol and testosterone here use LC/MS methodology, which offers greater accuracy at the low concentrations relevant to women and to men monitoring subtle changes. Ordering these five markers together in one draw is more efficient and less costly than piecing them together individually, and it gives you a coherent snapshot rather than disconnected data points.
For athletes & active people
For athletes, this axis is directly tied to recovery, adaptation, and training tolerance — heavy training loads, energy deficits, and inadequate rest can suppress LH, FSH, and testosterone, sometimes signaling under-recovery or relative energy deficiency before performance drops become obvious. Tracking free testosterone alongside SHBG and estradiol also helps active adults understand their anabolic environment and long-term hormonal health rather than chasing a single number. Used as a periodic check, it can flag when training stress may be outpacing recovery.
Order online
Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.
Get your sample collected
Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).
See your results
Your results land in your Insider portal, ready to review and act on — that easy.
Insider panel price
$156.47$420
2.7× less than retail
Versus the typical direct-to-consumer retail cost of ordering these tests individually (illustrative — consumer prices vary by provider and region). Your $20 order fee is waived as an Insider.
Peer-reviewed sources supporting the educational content on this page.