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Tryptase

This test measures total tryptase (alpha and beta tryptase). Tryptase is the most abundant protein component of human mast cell secretory granules. Serum levels generally reflect the extent of mast cell activation either by IgE- or non-IgE-mediated mechanisms.

From $55.00schedule~3d resultsbiotechAvailable at Labcorp · Quest
verifiedCLIA-certified labsmedical_services50-state physician networklocation_on4,000+ draw locations
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What this test reveals

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Tryptase measures mast cell activation in your body. Elevated levels can indicate allergic reactions, mast cell disorders, or systemic inflammation, helping clinicians identify why you might experience symptoms like hives, swelling, or anaphylaxis.

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What abnormal values may indicate

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When elevated: Elevated tryptase can indicate a mast cell disorder (such as mastocytosis), a severe allergic reaction (anaphylaxis), or other conditions involving mast cell activation. Levels may also rise temporarily during acute allergic episodes or certain inflammatory states. When low: Low tryptase levels are not clinically significant and do not indicate disease. Tryptase is primarily useful when elevated; a normal or low result generally rules out mast cell disorders.

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For athletes

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Not especially athlete-specific. However, intense exercise can trigger mast cell degranulation in some individuals, potentially causing exercise-induced anaphylaxis or urticaria. Tracking tryptase may help athletes with suspected exercise-related allergic symptoms identify whether mast cell activation is contributing to performance issues or post-workout reactions.

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Turnaround Time

3 days (up to 9 days)

scienceExpected Results

1 result
Tryptase
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How it works

  1. 1shopping_cart

    Order online

    Choose your lab and check out. We send your lab requisition automatically — no doctor visit needed.

  2. 2location_on

    Get your sample collected

    Visit a lab service center near you for a quick blood draw (or book at-home phlebotomy where available).

  3. 3monitoring

    See your results

    Your results land in your Insider portal, ready to review and act on — that easy.

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Your price

$55.00$165

Save ~$110

3.0× less than retail

Versus the typical direct-to-consumer retail price for this test (illustrative — consumer prices vary by provider and region).

LabcorpBest price

$55.00

Quest

$55.00

Frequently asked questions

What does the Tryptase test measure?

This test measures total tryptase (alpha and beta tryptase). Tryptase is the most abundant protein component of human mast cell secretory granules. Serum levels generally reflect the extent of mast cell activation either by IgE- or non-IgE-mediated mechanisms.

Why would I order the Tryptase test?

Tryptase measures mast cell activation in your body. Elevated levels can indicate allergic reactions, mast cell disorders, or systemic inflammation, helping clinicians identify why you might experience symptoms like hives, swelling, or anaphylaxis.

What can abnormal Tryptase results mean?

When elevated: Elevated tryptase can indicate a mast cell disorder (such as mastocytosis), a severe allergic reaction (anaphylaxis), or other conditions involving mast cell activation. Levels may also rise temporarily during acute allergic episodes or certain inflammatory states.

How much does the Tryptase test cost?

The Tryptase test starts at $55.00 at Labcorp or Quest. No doctor's visit and no insurance needed; we do not bill insurance. Fitomics Insider members pay from $49.97.

How long do Tryptase results take?

Results for the Tryptase test are typically ready about 3 days after your draw, and up to 9 days for some samples. Your results land in your Insider portal.

Do I need a doctor's order for the Tryptase test?

No. When you order the Tryptase test from Fitomics Research Labs, a licensed physician in our 50-state network reviews and signs your requisition after checkout, and it lands in your portal and inbox. Then visit any Labcorp, Quest, or BioReference patient service center for your draw; results post to your Insider portal.

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